In February 2019, researchers from the US developed an Artificial intelligence (AI) – powered platform in detecting neurodegenerative diseases. Scientists from the Icahn School of Medicine at Mount Sinai Hospital called the model the Precise Informatics Platform. Employing deep-learning algorithms, they were able to classify tauopathies like Alzheimer’s Disease and chronic traumatic encephalopathy.
AI for Precise Diagnoses
In their study titled Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy, the team used postmortem human brain samples from patients with different neurodegenerative diseases. The digitized images of sample tissues and human expert annotations were then utilized to “train” a deep learning convolutional neural network (FCN).
Lead investigator and Pathology and Neuroscience Professor John Crary says, “Utilizing artificial intelligence has great potential to improve our ability to detect and quantify neurodegenerative diseases, representing a major advance over existing labor-intensive and poorly reproducible approaches.”
AI for Improved Treatment Outcomes
The team explained that the model was to provide a solution for “obscure classifications and quantitative assessments” of abnormal tau in neurofibrillary tangles (NFT). These obscurities were caused by the tau protein’s diverse and overlapping morphological phenotypes. Thus, it’s difficult to accurately diagnose Alzheimer’s Disease and other neurodegenerative diseases.
This framework is deemed to have the potential to provide “unbiased data for clinicopathological correlations.” Co-author and Department of Pathology Chair Carlos Cordon-Cardo believes that with 80 million tests done in Mount Sinai Hospital every year, further research can lead to better diagnosis and patient outcomes.
Artificial intelligence offers countless solutions to many problems, but its further development remains controversial. Nevertheless, its benefits are palpable. With more advanced technology becoming available, more medical breakthroughs are achieved and that equates to more lives changed and saved.
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